对比FDA和CFDA批准的抗癌药物列表
对比FDA和CFDA批准的抗癌药物列表由刀豆文库小编整理，希望给你工作、学习、生活带来方便”。
对比FDA和CFDA批准的抗癌药物列表。
发现事实。下面的都是FDA批准的靶点药，而有中文名称的是CFDA允许在国内销售的。
可以说，国内病人基本享受不到自从05年以来的绝大多数抗癌研究成果。为父亲大人学习相关知识。
AgentTarget(s)FDA-approved indication(s)CFDA approved Ado-trastuzumab emtansine HER2(ERBB2/neu)(Kadcyla)EGFR(HER1/ERBB1), HER2 Afatinib(Gilotrif)(ERBB2/neu)Aldesleukin(Proleukin)
Alemtuzumab(Campath)Axitinib(Inlyta)Belimumab(Benlysta)Belinostat(Beleodaq)Bevacizumab(Avastin)
Bortezomib(Velcade)[1] |
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CD52 KIT, PDGFRβ, VEGFR1/2/3 BAFF HDAC VEGF ligand
Proteasomesubstitution(L858R)mutations)Renal cell carcinoma Melanoma
B-cell chronic lymphocytic leukemia Renal cell carcinoma Lupus erythematosus Peripheral T-cell lymphoma Cervical cancer
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Colorectal cancer Fallopian tube cancer Glioblastoma
Non-small cell lung cancer Ovarian cancer Peritoneal cancer Renal cell carcinoma Multiple myeloma
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Non-small cell lung cancer(with EGFR exon 19 deletions or exon
Breast cancer(HER2+)
Bosutinib(Bosulif)Brentuximab vedotin
ABL CD30
Mantle cell lymphoma
Chronic myelogenous leukemia(Philadelphia chromosome positive)Hodgkin lymphoma
Anaplastic large cell lymphoma Medullary thyroid cancer
(Adcetris)
Cabozantinib(Cometriq)VEGFR2 Canakinumab(Ilaris)
Carfilzomib(Kyprolis)IL-1β
Proteasome
Juvenile idiopathic arthritis
Cryopyrin-aociated periodic syndromes Multiple myeloma
FLT3, KIT, MET, RET, Ceritinib(Zykadia)Cetuximab(Erbitux)
Crizotinib(Xalkori)Dabrafenib(Tafinlar)Dasatinib(Sprycel)
Denosumab(Xgeva)Erlotinib(Tarceva)
Everolimus(Afinitor)
Gefitinib(Irea)Ibritumomab tiuxetan ALK EGFR(HER1/ERBB1)
ALK, MET BRAF ABL
RANKL EGFR(HER1/ERBB1)
mTOR
Non-small cell lung cancer(with ALK fusion)Colorectal cancer(KRAS wild type)
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Squamous cell cancer of the head and neck Non-small cell lung cancer(with ALK fusion)Melanoma(with BRAF V600 mutation)
Chronic myelogenous leukemia(Philadelphia chromosome positive)Acute lymphoblastic leukemia(Philadelphia chromosome positive)Giant cell tumor of the bone Non-small cell lung cancer
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Pancreatic cancer
Pancreatic neuroendocrine tumor Renal cell carcinoma
Nonresectable subependymal giant cell astrocytoma aociated with
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tuberous sclerosis
EGFR(HER1/ERBB1)
(limited approval)CD20(Zevalin)Ibrutinib(Imbruvica)|
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Mantle cell lymphoma
Non-Hodgkin's lymphoma
Breast cancer(HR+, HER2-)
Non-small cell lung cancer with known prior benefit from gefitinib
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Idelalisib(Zydelig)
Imatinib(Gleevec)
Ipilimumab(Yervoy)Lapatinib(Tykerb)
PI3Kδ
KIT, PDGFR, ABL
Chronic lymphocytic leukemia Chronic lymphocytic leukemia
Follicular B-cell non-Hodgkin lymphoma Small lymphocytic lymphoma GI stromal tumor(KIT+)Dermatofibrosarcoma protuberans
Multiple hematologic malignancies including Philadelphia
chromosome-positive ALL and CML CTLA-4 HER2(ERBB2/neu), EGFR
Breast cancer(HER2+)(HER1/ERBB1)
Chronic myelogenous leukemia(Philadelphia chromosome Nilotinib(Tasigna)Obinutuzumab(Gazyva)Ofatumumab(Arzerra, CD20 HuMax-CD20)Panitumumab(Vectibix)Pazopanib(Votrient)EGFR(HER1/ERBB1)VEGFR, PDGFR, KIT
Colorectal cancer(KRAS wild type)Renal cell carcinoma Melanoma
Breast cancer(HER2+)
Chronic lymphocytic leukemia
ABL
positive)CD20
Chronic lymphocytic leukemia
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Melanoma
Pembrolizumab(Keytruda)PD-1 Pertuzumab(Perjeta)HER2(ERBB2/neu)Ponatinib(Iclusig)
Ramucirumab(Cyramza)ABL, FGFR1-3, FLT3, VEGFR2 Chronic myelogenous leukemia
VEGFR2
Acute lymphoblastic leukemia(Philadelphia chromosome positive)
Gastric cancer or Gastroesophageal junction(GEJ)adenocarcinoma
Regorafenib(Stivarga)
Rituximab(Rituxan, Mabthera)
Romidepsin(Istodax)
Ruxolitinib(Jakafi)Siltuximab(Sylvant)Sipuleucel-T(Provenge)Sorafenib(Nexavar)
Temsirolimus(Torisel)Tocilizumab(Actemra)
Tofacitinib(Xeljanz)Tositumomab(Bexxar)Trametinib(Mekinist)Trastuzumab(Herceptin)
Vandetanib(Caprelsa)Vemurafenib(Zelboraf)Vismodegib(Erivedge)Vorinostat(Zolinza)Ziv-aflibercept(Zaltrap)KIT, PDGFRβ, RAF, RET, VEGFR1/2/3
CD20
HDAC
JAK1/2 IL-6
VEGFR, PDGFR, KIT, RAF
mTOR IL-6R
JAK3 CD20 MEK HER2(ERBB2/neu)
EGFR(HER1/ERBB1), RET, VEGFR2 BRAF PTCH, Smoothened HDAC PIGF, VEGFA/B
Colorectal cancer
Gastrointestinal stromal tumors Non-Hodgkin’s lymphoma
Chronic lymphocytic leukemia Rheumatoid arthritis
Granulomatosis with polyangiitis Cutaneous T-cell lymphoma Peripheral T-cell lymphoma Myelofibrosis
Multicentric Castleman's disease Prostate cancer
Hepatocellular carcinoma
Renal cell carcinoma Thyroid carcinoma Renal cell carcinoma Rheumatoid arthritis
Juvenile idiopathic arthritis Rheumatoid arthritis Non-Hodgkin's lymphoma
Melanoma(with BRAF V600 mutation)Breast cancer(HER2+)
Gastric cancer(HER2+)Medullary thyroid cancer
Melanoma(with BRAF V600 mutation)Basal cell carcinoma Cutaneous T-cell lymphoma Colorectal cancer
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