个人自传:生物物理(博士)_申请博士个人自述
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Biophysicsdevelofastwiththefruitsofmodernphysicsandchemistry.Thereisawiderangeoffascinatingquestioinunderstandinglifesystems.Duringtheseyears'studyatTsinghuaUniversity,Icotantlytriedtoimprovemyselfthroughindependentreading.ThiskeptmewellinformedofthelatestdevelopmentinBiophysicswhichattractsmealot.E.Schrodinger'sfamouswork“WhatisLife”l
etmethinkalotofquestioinBiophysics.Uptonow,physicisthavemadegreatsucceinstudyingsimpleperiodiccrystals,butforthecomplexbiologicalstructurespoebothaperiodicityandordersuchasDNA,therestillexistmanychallenges.Whytheseaperiodicmattercancontrolthelifestrictlyandprecisely?Whyasmallamountofnaturecatalyst-enzymecanbefarmoreefficientthanplentyofman-madecatalysts?Isthegrowthoflifedeterminedbygeneticmaterialsorbyself-aemblyorbybothofthem?Fromthebook“LiquidCrystalsandBiologicalStructures”writtenbyGleH.BrownandJeromeJ.Wolken,Igotdeeperunderstandingofbiologicalstructureswhichpoebothmobilityandlong-rangestructureorder,reondtoavarietyofexternalstimulijustlikethepropertiesofliquidcrystals.Thestrikingarchitectureatthemolecularlevelshowsthereisacommonphysical-chemicaloriginforalllifesystems.Theorientedmoleculesinliquidcrystalsfurnishanidealmediumforcatalyticaction,particularlyofthecomplextypeneededtoaccountforgrowthandreproduction.Water,eeciallytheweakhydrogenbondplayscriticalroleinallorganism.Itdeterminestheproteinfolding,stabilizesthedoublehelixstructureofDNA.Ifwesutitutedeuteriumforhydrogen,thebiologicalsystemmaybedestroyed.Manyphysicalandmathematicalaroachescanbealiedtobiologysuchasthequantummechanics,non-equilibriumthermodynamics,informationtheory.Butabasicdifficultbyusingthenon-equilibriumthermodynamicsinbiologyistheatialheterogeneityinbiologicalsystemsandthefeedbackexistinginallkindsofreactioandprocees.CondeedMatterPhysicsalsoconcercloselywithBiophysics.Thetheoryofphasetraitioandcriticalphenomenacanbeusedtoexplainproblemuchashowthetemperatureofthephasetraitionoflipidsfromthesolidstatetotheliquidcrystallinedependsonthefattyacidcomposition.Ontheotherhand,researchesinbiophysicsalsopushforwardthedevelopmentofphysics,leadtomorealicatioinbionicuchasAIandneuralnetwork
NowIamdoingmyDiplomaThesisattheItituteofPhysics,ChineseAcademyofS
cience.MyTopicisaboutinvestigatingcoherentbackscatteringinarandomscatteringmediumbytheHe-Newlaser.Lightincertaindielectricmicrostructuresexhibitslocalizedmodes,similartothelocalizedwavefunctionofelectroindisorderedsolids-AndersonLocalization.Thepropagationoflightinascatteringmediumcanbedescribedasrandomwalkofphotowiththedirectionofeachsucc
eedingstepdeterminedbythelawsofprobability.TheTopicathedisciplinesofCondeedMatterPhysicsandQuantumOpties.Ihaveaorbedalotofrelativeknowledgesuchasrandomwalk,perorationmodeltochasticprocetoprepareformyproject.IthinkthemethodIdynamicsofchemicalreactio.Sincemybackgroundfocusedonphysics,mathematics,electronics,lasersandoptics,Ihavetaughtmyselfsomebegiingbiologyandchemistrycoursesthisyear,discuedthemwithteachersintheDeptofBiologicalScienceandTechnologyatTsinghuaUniversityIwouldalsoliketotakemorebasiccoursesinthisfieldunderyourguidancetomakeupmydeficiency.FromcollegeguidesIlearnedwithpleasurethatyouhadstrongfacultywithavarietyofbackgroundinphysics,chemistry,mathematicsandelectricalengineering.Itisofteninthemulti-disciplinaryresearchthatcamethemostexcitingdiscovery.Yourgroupalsoprovidesoutstandingoortunitiesforcloseinteractionbetweengraduatestudentsandfaculty.ThatiswhyIdeemyourprogramasmybestchoice.Besides,IwanttolinkmodernbiophysicswithChineseMedicinetogetcompreheiveunderstandingoflife.